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Home »Product center » Intermediates » Intermediates » AZD-9291 (Mesylate)

AZD-9291 (Mesylate)

 

Cat. No.: BY00020
Product Name: AZD-9291 (Mesylate)
Synonyms: N-[2-(2-dimethylaminoethylmethylamino)-4-methoxy- 5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide mesylate salt; AZD9291 mesylate; AZD-9291 mesylate; AZD 9291 mesylate;N-(2-{2-dimethylaminoethyl-methylamino}-4-methoxy-5-{[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide mesylate
IUPAC Name: N-[2-[2-(dimethylamino)ethyl-methylamino]-4- methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide;methanesulfonic acid
CAS NO.: 1421373-66-1
Molecular Formula: C28H33N7O2.CH4O3S
Molecular Weight: 595.71
Purity: 99%+
Supply Capacity: mg to kgs

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COA MSDS


Delivery Time(in stock products)

Within three or four working days.


Reference information
InChI Key: FUKSNUHSJBTCFJ-UHFFFAOYSA-N
Reaxys Registry Number: 23334374
Pub CID: 78357807
Canonical SMILES: CS(O)(=O)=O.COC1=C(NC2=NC=CC(=N2)C2=CN(C)C3=C2C=CC=C3)C=C(NC (=O)C=C)C(=C1)N(C)CCN(C)C
References: Article; Finlay, M. Raymond V.; Anderton, Mark; Ashton, Susan; Ballard, Peter; Bethel, Paul A.; Box, Matthew R.; Bradbury, Robert H.; Brown, Simon J.; Butterworth, Sam; Campbell, Andrew; Chorley, Christopher; Colclough, Nicola; Cross, Darren A. E.; Currie, Gordon S.; Grist, Matthew; Hassall, Lorraine; Hill, George B.; James, Daniel; James, Michael; Kemmitt, Paul; Klinowska, Teresa; Lamont, Gillian; Lamont, Scott G.; Martin, Nathaniel; McFarland, Heather L.; Mellor, Martine J.; Orme, Jonathon P.; Perkins, David; Perkins, Paula; Richmond, Graham; Smith, Peter; Ward, Richard A.; Waring, Michael J.; Whittaker, David; Wells, Stuart; Wrigley, Gail L.; Journal of Medicinal Chemistry; vol. 57; 20; (2014); p. 8249 - 8267;
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; BUTTERWORTH, Sam; FINLAY, Maurice, Raymond, Verschoyle; WARD, Richard, Andrew; KADAMBAR, Vasantha, Krishna; CHANDRASHEKAR, Reddy, C.; MURUGAN, Andiappan; REDFEARN, Heather, Marie; WO2013/14448; (2013); A1;

 

 

Appearance: yellow powder Solvent: N/A   
Melting Point: 246 - 259℃ Optical Rotation: N/A
Boiling Point: N/A Density: N/A
Packaging: Amber glass bottle, white plastic bottle Storage Condition: Store in room temperature

 

For research use only. Not as drugs for human and animals.
 
 

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