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Home »Product center » Intermediates » Intermediates » Canagliflozin intermediate
32384-65-9

Canagliflozin intermediate
32384-65-9

 

Cat. No.: BY30002
Product Name: Canagliflozin Intermediate
Synonyms: (3R,4S,5R,6R)-3,4,5-tris((trimethylsilyl)oxy)
-6-(((trimethylsilyl)oxy)methyl)tetrahydro
-2H-pyran-2-one;  (3R,4S,5R,6R)-3,4,5
-tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)
tetrahydro-2H-pyran-2-one; (3R,4S,5R,6R)-3,4,5
-tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)
tetrahydropyran-2-one; (3R,4S,5R,6R)-3,4,5
-tris(trimethylsilyloxy)-6-trimethylsilyloxymethyltetrahydro-2H-pyran-2-one; (3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-
trimethylsilyloxymethyl)tetrahydropyran
-2-one; 2,3,4,6-tetrakis-O-(trimethylsilyl)-D
-glucono-1,5-lactone; 2,3,4,6-tetra-O-trimethylsilyl-delta-D-gluconolactone
IUPAC Name: (3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6
-(trimethylsilyloxymethyl)oxan-2-one
CAS NO.: 32384-65-9
Molecular Formula: C18H42O6Si4
Molecular Weight: 466.86448
Purity: 99%+
Supply Capacity: mg to kgs

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COA MSDS


Delivery Time(in stock products)

Within three or four working days.


Reference information
InChI Key: VNGTZLYNGGLPIZ-WCXIOVBPSA-N
Reaxys Registry Number: 5136973
Pub CID: 10994280
Canonical SMILES: C[Si](C)(C)OCC1C(C(C(C(=O)O1)O[Si](C)(C)C)O[Si](C)(C)C)O[Si](C)(C)C
References: Article; Ohba, Kiyomi; Koga, Yuichi; Nomura, Sumihiro; Nakata, Masaya; Tetrahedron Letters; vol. 56; 8; (2015); p. 1007 - 1010;
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Article; Guo, Cheng; Hu, Min; Deorazio, Russell J.; Usyatinsky, Alexander; Fitzpatrick, Kevin; Zhang, Zhenjun; Maeng, Jun-Ho; Kitchen, Douglas B.; Tom, Susan; Luche, Michele; Khmelnitsky, Yuri; Mhyre, Andrew J.; Guzzo, Peter R.; Liu, Shuang; Bioorganic and Medicinal Chemistry; vol. 22; 13; (2014); p. 3414 - 3422;
Article; Horton, Derek; Priebe, Waldemar; Carbohydrate Research; vol. 94; (1981); p. 27 - 42;
Patent; Mitsubishi Tanabe Pharma Corporation; US2008/146515; A1; (2008);
Patent; Deshpande, Prashant P.; Ellsworth, Bruce A.; Singh, Janak; Denzel, Theodor W.; Lai, Chiajen; Crispino, Gerard; Randazzo, Michael E.; Gougoutas, Jack Z.; US2004/138439; A1; (2004);
Article; Bernhardson, David; Brandt, Thomas A.; Hulford, Catherine A.; Lehner, Richard S.; Preston, Brian R.; Price, Kristin; Sagal, John F.; Pierre, Michael J. St.; Thompson, Peter H.; Thuma, Benjamin; Organic Process Research and Development; vol. 18; 1; (2014); p. 57 - 65;
Patent; THERACOS, INC.; XU, Baihua; LV, Binhua; XU, Ge; SEED, Brian; ROBERGE, Jacques; WO2013/152476; A1; (2013);
Article; Wang, Xiao-Jun; Zhang, Li; Byrne, Denis; Nummy, Larry; Weber, Dirk; Krishnamurthy, Dhileep; Yee, Nathan; Senanayake, Chris H.; Organic Letters; vol. 16; 16; (2014); p. 4090 - 4093;

 

 

Appearance: light yellow powder Solvent: CHCl3   
Melting Point: 128 - 129℃ Optical Rotation: N/A
Boiling Point: N/A Density: N/A
Packaging: Amber glass bottle, white plastic bottle Storage Condition: Store in room temperature

 

Note: Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes patent infringement and its liability is at buyer’s risk.
 
 

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