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Home »Product center » Intermediates » Intermediates » Cabozantinib(XL184)
849217-68-1

Cabozantinib(XL184)
849217-68-1

 

Cat. No.: BY00021
Product Name: Cabozantinib(XL184)
Synonyms: [14C]-CabozantinibCabozantinibcyclopropane-1,1- dicarboxylic acid [4-(6,7-dimethoxy-quinoline-4-yloxy)-phenyl]-amide (4-fluoro-phenyl)-amide; cyclopropane-1,1-dicarboxylic acid [4- (6,7-dimethoxy-quinoline-4-yloxy)phenyl]amide(4-fluorophenyl)amide; cyclopropane-1,1-dicarboxylic acid [4-(6,7-dimethoxyquinoline-4yloxy)phenyl]amide(4-fluorophenyl)amide; Cometriq?; cabozantinib
IUPAC Name: 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4 -fluorophenyl)cyclopropane-1,1-dicarboxamide
CAS No.: 849217-68-1
Molecular Formula: C28H24FN3O5
Molecular Weight: 502
Purity: 99%+
Supply Capacity: g to kgs

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COA MSDS


Delivery Time(in stock products)

Within three or four working days.


Reference information
InChI Key: ONIQOQHATWINJY-UHFFFAOYSA-N
Reaxys Registry Number: 18631644
Pub CID: 25102847
Canonical SMILES: COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C (C=C5)F
References: Article; She, Nengfang; Zhuo, Linsheng; Jiang, Wen; Zhu, Xiaolei; Wang, Jia; Ming, Zhihui; Zhao, Xinge; Cong, Xin; Huang, Wei; Bioorganic and Medicinal Chemistry Letters; vol. 24; 15; (2014); p. 3351 - 3355;
Patent; EXELIXIS, INC.; SWEENEY, Christopher J.; KANTOFF, Philip W.; WO2014/165779; (2014); A1;
Article; Jiang, Xiaolong; Liu, Hongyan; Song, Zilan; Peng, Xia; Ji, Yinchun; Yao, Qizheng; Geng, Meiyu; Ai, Jing; Zhang, Ao; Bioorganic and Medicinal Chemistry; vol. 23; 3; (2015); p. 564 - 578;
Patent; EXELIXIS, INC.; AFTAB, Dana, T; SCHIMMOLLER, Frauke; WO2013/70890; (2013); A1;
Patent; EXELIXIS, INC.; AFTAB, Dana, T.; WO2013/166296; (2013); A1;
Patent; EXELIXIS, INC.; DECILLIS, Arthur; WO2014/165786; (2014); A1;
Patent; EXELIXIS, INC.; AFTAB, Dana, T.; NAGANATHAN, Sriram; XU, Wei; LACY, Steven; NGUYEN, Linh; WO2014/145715; (2014); A1;
Patent; EXELIXIS, INC.; WILSON, Jo, Ann; NAGANATHAN, Sriram; PFEIFFER, Matthew; ANDERSEN, Neil, G.; WO2013/59788; (2013); A1;
Patent; EXELIXIS, INC.; AFTAB, Dana, T.; CLARY, Douglas; WO2013/43840; (2013); A1;
Patent; EXELIXIS, INC.; WILSON, Jo Ann; WO2012/109510; (2012); A1;

 

 

Appearance: white powder Solvent: dimethylsulfoxide-d6   
Melting Point: N/A Optical Rotation: N/A
Boiling Point: N/A Density: N/A
Packaging: aluminum foil bag, white plastic bottle Storage Condition: Store in room temperature

 

Note: Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes patent infringement and its liability is at buyer's risk.
 
 
 

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