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Home »Product center » Intermediates » Intermediates » Sofosbuvir intermediate
863329-66-2

Sofosbuvir intermediate
863329-66-2

 

Cat. No.: BY30025
Product Name: Sofosbuvir intermediate
Synonyms: beta-D-2'-deoxy-2'-alpha-F-2'-beta-C-methyluridine; 1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-hydroxymethyl-3-methyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione; 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl]pyrimidine-2,4-dione; beta-D-2'-deoxy-2'-alpha-fluoro-2'-C-methyluridine; 2'-deoxy-2'-alpha-fluoro-2'-beta-C-methyluridine; beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine
IUPAC Name: 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione
CAS NO.: 863329-66-2
Molecular Formula: C10H13FN2O5
Molecular Weight: 260.2
Purity: 99%+
Supply Capacity: mg to kgs

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COA MSDS


Delivery Time(in stock products)

Within three or four working days.


Reference information
InChI Key: ARKKGZQTGXJVKW-VPCXQMTMSA-N
Reaxys Registry Number: 10267735
Pub CID: 11311503
Canonical SMILES: CC1(C(C(OC1N2C=CC(=O)NC2=O)CO)O)F
References: Patent; MAYES, Benjamin Alexander; MOUSSA, Adel M.; DOUSSON, Cyril B.; GOSSELIN, Gilles; PIERRA, Claire; DUKHAN, David; US2015/37282; A1; (2015);
Article; Kirschberg, Thorsten A.; Mish, Michael R.; Zhang, Lijun; Squires, Neil H.; Wang, Ke-Yu; Cho, Aesop; Feng, Joy Y.; Fenaux, Martijn; Babusis, Darius; Park, Yeojin; Ray, Adrian S.; Kim, Choung U.; Bioorganic and Medicinal Chemistry Letters; vol. 25; 5; (2015); p. 1046 - 1049;
Patent; MOUSSA, Adel M.; MAYES, Benjamin Alexander; ARUMUGASAMY, Jeevanandam; WANG, Jingyang; US2014/112886; A1; (2014);
Patent; ALIOS BIOPHARMA, INC.; Beigelman, Leonid; Wang, Guangyi; Smith, David Bernard; US2014/179627; A1; (2014);
Patent; VERTEX PHARMACEUTICALS INCORPORATED; ROSE, Peter, Jamison; JUNG, Young, Chun; BLIGH, Cavan, Mckeon; IBRAHIM, Shereen; ANZALONE, Luigi; MILLER, David, B.; VAN ALSTEN, John, Gregg; CURRAN, Timothy, Thomas; WO2014/164533; A1; (2014);

 

 

Appearance: white powder Solvent: methanol   
Melting Point: 237.3 - 238℃ Optical Rotation: N/A
Boiling Point: N/A Density: N/A
Packaging: Amber glass bottle, white plastic bottle Storage Condition: Store in room temperature

 

Note: Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes patent infringement and its liability is at buyer’s risk.
 
 

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