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Home »Product center » Intermediates » Intermediates » Sofosbuvir intermediate
874638-80-9

Sofosbuvir intermediate
874638-80-9

 

Cat. No.: BY30028
Product Name: Sofosbuvir intermediate
Synonyms: 3,5-di-O-benzoyl-2-deoxy-2-fluoro-2-C-methyl-D-ribono-gamma-lactone; ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate; ((2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxo-tetrahydrofuran-2-yl)methyl benzoate; ((3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate; (2R)-2-deoxy-2-fluoro-2-methyl-D-ribono-1,4-lactone-3,5-dibenzoate; (2R)-3,5-di-O-benzoyl-2-fluoro-2-C-methyl-D-ribono-gamma-lactone; 3,5-dibenzoyl-2-deoxy-2-fluoro-2-C-methyl-D-ribono-1,4-lactone
IUPAC Name: [(2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxooxolan-2-yl]methyl benzoate
CAS NO.: 874638-80-9
Molecular Formula: C20H17FO6
Molecular Weight: 372.3
Purity: 99%+
Supply Capacity: mg to kgs

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COA MSDS


Delivery Time(in stock products)

Within three or four working days.


Reference information
InChI Key: OUKYMZJNLWKCSO-JXXFODFXSA-N
Reaxys Registry Number: 12673852
Pub CID: 42625091
Canonical SMILES: CC1(C(C(OC1=O)COC(=O)C2=CC=CC=C2)OC(=O)C3=CC=CC=C3)F
References: Article; Kirschberg, Thorsten A.; Mish, Michael R.; Zhang, Lijun; Squires, Neil H.; Wang, Ke-Yu; Cho, Aesop; Feng, Joy Y.; Fenaux, Martijn; Babusis, Darius; Park, Yeojin; Ray, Adrian S.; Kim, Choung U.; Bioorganic and Medicinal Chemistry Letters; vol. 25; 5; (2015); p. 1046 - 1049;
Patent; ALIOS BIOPHARMA, INC.; Beigelman, Leonid; Wang, Guangyi; Smith, David Bernard; US2014/179627; A1; (2014);
Patent; Gilead Sciences, Inc.; US2011/70194; A1; (2011);
Patent; GILEAD SCIENCES, INC.; BUTLER, Thomas; CHO, Aesop; GRAETZ, Benjamin, R.; KIM, Choung, U.; METOBO, Samuel, E.; SAUNDERS, Oliver, L.; WALTMAN, Andrew, W.; XU, Jie; ZHANG, Lijun; WO2011/35250; A1; (2011);
Patent; PHARMASSET, INC.; US2010/16251; A1; (2010);
Patent; PHARMASSET, INC.; BAO, Donghui; CHANG, Wosnuk; NAGARATHNAM, Dhanapalan; SOFIA, Michael, Joseph; WO2010/75517; A2; (2010);

 

 

Appearance: white powder Solvent: isopropyl alcohol   
Melting Point: 132.9 - 133.1℃ Optical Rotation: N/A
Boiling Point: N/A Density: N/A
Packaging: Amber glass bottle, white plastic bottle Storage Condition: Store in room temperature

 

Note: Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes patent infringement and its liability is at buyer’s risk.
 
 

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