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Cat. No.: BY30113
Product Name: N-[(2R,3S)-2-(2,5-Difluorophenyl)tetrahydro-5-oxo-2H-pyran-3-yl]carbamic acid 1,1-dimethylethyl ester
Synonyms: MK-3102 intermediate MK-3102 中间体;tert-butyl ((2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbamate; tert-butyl [(2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro- 2H-pvran-3 yl]carbamate; tert-butyl [(2R,3S)-5-oxo-2-(2,5-difluorophenyl)tetrahydro-2H-pyran-3-yl]carbamate; tert-butyl ((2R3S)-2- (2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbamate; tert-butyl [(2R,3S)-5-oxo-2-(2,5-difluorophenyl)tetradihydro-2H-pyran-3 -yl]carbamate; tert-butyl [(2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl]carbamate; tert-butyl [(2R,5S)-5-oxo-2-(2,5- difluorophenyl)tetrahydro-2H-pyran-3-yl]carbamate
IUPAC Name: tert-butyl N-[(2R,3S)-2-(2,5-difluorophenyl)-5- oxooxan-3-yl]carbamate
CAS No.: 951127-25-6
Molecular Formula: C16H19F2NO4
Molecular Weight: 327.32
Purity: 99%+
Supply Capacity: g to kgs



Delivery Time(in stock products)

Within three or four working days.

Reference information
Reaxys Registry Number: 15561295
Pub CID: 44193925
Canonical SMILES: CC(C)(C)OC(=O)N[C@H]1CC(=O)CO[C@@H]1C1=C(F)C=CC(F) =C1
References: Patent; MERCK SHARP and DOHME CORP.; BIFTU, Tesfaye; KHAN, Tanweer, A.; WO2014/18355; (2014); A1;
Patent; CADILA HEALTHCARE LIMITED; DESAI, Ranjit, C.; BAHEKAR, Rajesh; JADAV, Pradip; GOSWAMI, Amitgiri; PATEL, Pankaj; WO2014/61031; (2014); A1;
Article; Biftu, Tesfaye; Sinha-Roy, Ranabir; Chen, Ping; Qian, Xiaoxia; Feng, Dennis; Kuethe, Jeffrey T.; Scapin, Giovanna; Gao, Ying Duo; Yan, Youwei; Krueger, Davida; Bak, Annette; Eiermann, George; He, Jiafang; Cox, Jason; Hicks, Jacqueline; Lyons, Kathy; He, Huaibing; Salituro, Gino; Tong, Sharon; Patel, Sangita; Doss, George; Petrov, Aleksandr; Wu, Joseph; Xu, Shiyao Sherrie; Sewall, Charles; Zhang, Xiaoping; Zhang, Bei; Thornberry, Nancy A.; Weber, Ann E.; Journal of Medicinal Chemistry; vol. 57; 8; (2014); p. 3205 - 3212;
Article; Xu, Feng; Zacuto, Michael J.; Kohmura, Yoshinori; Rosen, Jon; Gibb, Andrew; Alam, Mahbub; Scott, Jeremy; Tschaen, David; Organic Letters; vol. 16; 20; (2014); p. 5422 - 5425;
Article; Biftu, Tesfaye; Qian, Xiaoxia; Chen, Ping; Feng, Dennis; Scapin, Giovanna; Gao, Ying-Duo; Cox, Jason; Sinha Roy, Ranabir; Eiermann, George; He, Huabing; Lyons, Kathy; Salituro, Gino; Patel, Sangita; Petrov, Alexander; Xu, Feng; Xu, Shiyao Sherrie; Zhang, Bei; Caldwell, Charles; Wu, Joseph K.; Weber, Ann E.; Bioorganic and Medicinal Chemistry Letters; vol. 23; 19; (2013); p. 5361 - 5366;
Patent; MERCK SHARP and DOHME CORP.; ARROYO, Itzia; KRUEGER, Davida; CHEN, Ping; MOMENT, Aaron; BIFTU, Tesfaye; SHEEN, Faye; ZHANG, Yanfeng; MERCK SHARPE and DOHME LTD.; WO2013/3249; (2013); A1;
Patent; Biftu, Tesfaye; Weber, Ann E.; US2007/232676; (2007); A1;
Patent; Biftu, Tesfaye; Chen, Ping; Cox, Jason M.; Weber, Ann E.; US2010/120863; (2010); A1;
Patent; MERCK SHARP and DOHME CORP.; BIFTU, Tesfaye; CHEN, Ping; FENG, Danqing; QIAN, Xiaoxia; WO2011/28455; (2011); A1;



Appearance: white powder Solvent: chloroform   
Melting Point: N/A Optical Rotation: N/A
Boiling Point: N/A Density: N/A
Packaging: aluminum foil bag or white plastic bottle Storage Condition: Store in room temperature


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