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Sofosbuvir intermediate


Cat. No.: BY30027
Product Name: Sofosbuvir intermediate
Synonyms: N4,3',5'-tri-O-benzoyl-2'-deoxy-2'-fluoro-2'-C-methylcytidine; 3',5'-O-N(4)-tribenzoyl-2'-deoxy-2'-fluoro-2'-C-methylcytidine; (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-(benzoyloxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate; N4-benzoyl-1-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-2'-C-methyl-beta-D-ribofuranosyl)cytosine; (2?R)-N-benzoyl-2?-deoxy-2?-fluoro-2?-methylcytidine-3?,5?-dibenzoate; (2'R)-N-benzoyl-2'-deoxy-2'-fluoro-2'-methyl-cytidine-3',5'-dibenzoate; N4-benzoyl-3',5'-di-O-benzoyl-2'-fluoro-2'-C-methylcytidine
IUPAC Name: [(2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1-yl)-3-benzoyloxy-4-fluoro-4-methyloxolan-2-yl]methyl benzoate
CAS NO.: 817204-32-3
Molecular Formula: C31H26FN3O7
Molecular Weight: 571.6
Purity: 99%+
Supply Capacity: mg to kgs



Delivery Time(in stock products)

Within three or four working days.

Reference information
Reaxys Registry Number: 10310679
Pub CID: 11330583
Canonical SMILES: CC1(C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(=O)C4=CC=CC=C4)OC(=O)C5=CC=CC=C5)F
References: Patent; ENANTA PHARMACEUTICALS, INC.; OR, Yat Sun; MA, Jun; WANG, Guoqiang; WO2013/173759; A2; (2013);
Patent; GILEAD SCIENCES, INC.; Delaney, William E.; Link, John O.; Mo, Hongmei; Oldach, David W.; Ray, Adrian S.; Watkins, William J.; Yang, Cheng Yong; Zhong, Weidong; US2013/273005; A1; (2013);
Patent; PHARMASSET, INC.; ROSS, Bruce, S.; SOFIA, Michael, Joseph; PAMULAPATI, Ganapati, Reddy; RACHAKONDA, Suguna; ZHANG, Hai-ren; CHUN, Byoung-kwon; WANG, Peiyuan; WO2010/135569; A1; (2010);
Patent; PHARMASSET, INC.; F. HOFFMANN LA-ROCHE AG; WO2008/45419; A1; (2008);
Article; Clark, Jeremy L.; Mason, J. Christian; Hobbs, Ann J.; Hollecker, Laurent; Schinazi, Raymond F.; Journal of Carbohydrate Chemistry; vol. 25; 6; (2006); p. 461 - 470;
Article; Clark, Jeremy L.; Hollecker, Laurent; Mason, J. Christian; Stuyver, Lieven J.; Tharnish, Phillip M.; Lostia, Stefania; McBrayer, Tamara R.; Schinazi, Raymond F.; Watanabe, Kyoichi A.; Otto, Michael J.; Furman, Phillip A.; Stec, Wojciech J.; Patterson, Steven E.; Pankiewicz, Krzysztof W.; Journal of Medicinal Chemistry; vol. 48; 17; (2005); p. 5504 - 5508;



Appearance: white powder Solvent: CH2Cl2; hexane   
Melting Point: 240 - 241℃ Optical Rotation: N/A
Boiling Point: N/A Density: N/A
Packaging: Amber glass bottle, white plastic bottle Storage Condition: Store in room temperature


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